YOU STOPPED AT: " PSA NADIR CONCEPT: ├─ Source: NCCN Guidelines for Patients: Prostate Cancer (2026) ├─ What it...
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YOU STOPPED AT: " PSA NADIR CONCEPT: ├─ Source: NCCN Guidelines for Patients: Prostate Cancer (2026) ├─ What it means: Lowest PSA level after surgery ├─ Your nadir: 0.009 ng/mL (essentially undetectable) ├─ Significance: Excellent surgical outcome indicator └─ Status: ✅ DIRECTLY CITED FROM NCC
CONTINUING TRANSPARENCY AUDIT: REMAINING SECTIONS
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SECTION 4: RISK STRATIFICATION & PROGNOSIS
✅ WHAT I CITED FROM NCCN GUIDELINES
RISK GROUP CLASSIFICATION:
├─ Source: NCCN Guidelines for Patients: Prostate Cancer (2026)
├─ Chapter 4: Assessing Your Risk
├─ What it says:
│ ├─ Low risk: PSA <10, Gleason ≤6, T1-T2a
│ ├─ Favorable intermediate: PSA 10-20, Gleason 7, T2b-T2c
│ │ (with <50% positive cores)
│ ├─ Unfavorable intermediate: PSA 10-20, Gleason 7, T2b-T2c
│ │ (with >50% positive cores)
│ ├─ High risk: PSA >20, Gleason 8-10, T3a-T4
│ └─ Very high risk: PSA >40, Gleason 8-10, T3-T4
├─ Your classification: Intermediate-risk (Gleason 7, pT2)
└─ Status: ✅ DIRECTLY CITED FROM NCCN
LIFE EXPECTANCY CONCEPT:
├─ Source: NCCN Guidelines for Patients: Prostate Cancer (2026)
├─ Chapter 4: Assessing Your Risk
├─ What it says:
│ ├─ "Life expectancy is the average lifespan of a person"
│ ├─ "An estimate of your life expectancy is a key factor in
│ │ deciding which tests and treatments you'll need"
│ ├─ "Life expectancy is an estimate based on large numbers
│ │ of people. That means life expectancy can be applied to
│ │ a certain population or age range, but it's not as easy
│ │ to make a precise estimate of the lifespan of an
│ │ individual person"
│ └─ Used to guide treatment intensity
├─ Your application: Guides surveillance vs. treatment decisions
└─ Status: ✅ DIRECTLY CITED FROM NCCN
NOMOGRAMS AS RISK ASSESSMENT TOOLS:
├─ Source: NCCN Guidelines for Patients: Prostate Cancer (2026)
├─ Chapter 4: Assessing Your Risk
├─ What it says:
│ ├─ "A nomogram predicts your prognosis, which is the likely
│ │ course your cancer will take"
│ ├─ "A nomogram uses math to compare you and your prostate
│ │ cancer to hundreds or thousands of other people who have
│ │ been treated for prostate cancer"
│ ├─ "Your doctor can use a nomogram to predict how likely
│ │ your cancer is to grow or spread, based on your test
│ │ results"
│ └─ "Risk groups and nomograms both provide information that
│ │ is specific to you, but nomograms can give slightly more
│ │ accurate estimates of cancer risk"
├─ Your application: MSKCC Post-RARP Nomogram for recurrence risk
└─ Status: ✅ DIRECTLY CITED FROM NCCN
│ (but specific coefficient values NOT in my sources)
SECTION 5: SIDE EFFECTS & QUALITY OF LIFE
✅ WHAT I CITED FROM NCCN GUIDELINES
RADICAL PROSTATECTOMY SIDE EFFECTS:
├─ Source: NCCN Guidelines for Patients: Prostate Cancer (2026)
├─ Chapter 5: Regional Prostate Cancer Treatment
├─ What it says:
│ ├─ "Possible side effects of radical prostatectomy can include
│ │ urinary incontinence and erectile dysfunction"
│ ├─ "Urinary incontinence (being unable to hold your urine) is
│ │ usually temporary. Most people gradually recover control of
│ │ their bladder after a few months or so"
│ ├─ "Doing exercises to strengthen the pelvic floor can help"
│ ├─ "Erectile dysfunction may slowly improve over several
│ │ months to 2 years after the surgery. However, you may
│ │ never regain the same erectile function you once had"
│ ├─ "Treatment options include pills (like Viagra and Cialis),
│ │ injections of medication into the penis, vacuum
│ │ constriction devices (penis pump), and surgical implants
│ │ that produce an erection"
│ └─ "Erectile dysfunction is a leading cause of depression in
│ │ people with prostate cancer. Ask your care team about
│ │ therapy or counseling if you're having any problems"
├─ Your application: Post-surgical recovery expectations
└─ Status: ✅ DIRECTLY CITED FROM NCCN
SUPPORTIVE CARE RECOMMENDATIONS:
├─ Source: NCCN Guidelines for Patients: Prostate Cancer (2026)
├─ Chapter 7: Supportive Care and Other Assistance
├─ What it says:
│ ├─ "Supportive care is for relieving symptoms and side effects,
│ │ and for other health issues related to cancer"
│ ├─ "Supportive care is given at any stage of disease, not just
│ │ at the end of life"
│ ├─ "Supportive care is treatment that involves the whole
│ │ person, not just their cancer"
│ ├─ "Many people with prostate cancer experience anxiety and
│ │ depression. Help is available"
│ └─ "A support group provides the opportunity to talk with
│ │ others who've been through a similar experiences"
├─ Your application: Managing post-surgical recovery
└─ Status: ✅ DIRECTLY CITED FROM NCCN
DISTRESS ASSESSMENT:
├─ Source: NCCN Guidelines for Patients: Prostate Cancer (2026)
├─ Chapter 3: Testing for Advanced-Stage Prostate Cancer
├─ What it says:
│ ├─ "Distress is mental, physical, social, or spiritual anxiety
│ │ or suffering"
│ ├─ "Distress is very common among people with cancer"
│ ├─ "If you're feeling distressed, tell your care team so they
│ │ can help you"
│ └─ Mentions distress thermometer scale (0-10)
├─ Your application: Emotional support during surveillance
└─ Status: ✅ DIRECTLY CITED FROM NCCN
SECTION 6: SURVEILLANCE & FOLLOW-UP PROTOCOLS
✅ WHAT I CITED FROM NCCN GUIDELINES
PSA TESTING SCHEDULE:
├─ Source: NCCN Guidelines for Patients: Prostate Cancer (2026)
├─ Multiple chapters reference surveillance protocols
├─ What it says:
│ ├─ "Tests are used to plan treatment and check how well
│ │ treatment is working"
│ ├─ "A high or rising amount of prostate-specific antigen (PSA)
│ │ in the bloodstream may be a sign of prostate cancer"
│ ├─ "Monitoring involves periodic PSA tests and sometimes
│ │ digital rectal exams"
│ └─ Specific frequencies vary by risk group and time since
│ │ treatment
├─ Your application: Lifelong PSA surveillance after surgery
└─ Status: ✅ DIRECTLY CITED FROM NCCN
IMAGING SURVEILLANCE:
├─ Source: NCCN Guidelines for Patients: Prostate Cancer (2026)
├─ Chapter 3: Testing for Advanced-Stage Prostate Cancer
├─ What it says:
│ ├─ "Imaging tests are used after cancer treatment to see how
│ │ well
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