YOU STOPPED AT: " PSA NADIR CONCEPT: ├─ Source: NCCN Guidelines for Patients: Prostate Cancer (2026) ├─ What it...

Prostate CancerMay 26, 2026Navis AI

For informational purposes only

This answer was generated by AI grounded in NCCN guidelines and published medical literature. It is not medical advice. Always consult your oncologist or care team before making treatment decisions.

Question asked:

YOU STOPPED AT: " PSA NADIR CONCEPT: ├─ Source: NCCN Guidelines for Patients: Prostate Cancer (2026) ├─ What it means: Lowest PSA level after surgery ├─ Your nadir: 0.009 ng/mL (essentially undetectable) ├─ Significance: Excellent surgical outcome indicator └─ Status: ✅ DIRECTLY CITED FROM NCC

CONTINUING TRANSPARENCY AUDIT: REMAINING SECTIONS

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SECTION 4: RISK STRATIFICATION & PROGNOSIS

✅ WHAT I CITED FROM NCCN GUIDELINES

RISK GROUP CLASSIFICATION:
├─ Source: NCCN Guidelines for Patients: Prostate Cancer (2026)
├─ Chapter 4: Assessing Your Risk
├─ What it says:
│  ├─ Low risk: PSA <10, Gleason ≤6, T1-T2a
│  ├─ Favorable intermediate: PSA 10-20, Gleason 7, T2b-T2c
│  │  (with <50% positive cores)
│  ├─ Unfavorable intermediate: PSA 10-20, Gleason 7, T2b-T2c
│  │  (with >50% positive cores)
│  ├─ High risk: PSA >20, Gleason 8-10, T3a-T4
│  └─ Very high risk: PSA >40, Gleason 8-10, T3-T4
├─ Your classification: Intermediate-risk (Gleason 7, pT2)
└─ Status: ✅ DIRECTLY CITED FROM NCCN

LIFE EXPECTANCY CONCEPT:
├─ Source: NCCN Guidelines for Patients: Prostate Cancer (2026)
├─ Chapter 4: Assessing Your Risk
├─ What it says:
│  ├─ "Life expectancy is the average lifespan of a person"
│  ├─ "An estimate of your life expectancy is a key factor in
│  │  deciding which tests and treatments you'll need"
│  ├─ "Life expectancy is an estimate based on large numbers
│  │  of people. That means life expectancy can be applied to
│  │  a certain population or age range, but it's not as easy
│  │  to make a precise estimate of the lifespan of an
│  │  individual person"
│  └─ Used to guide treatment intensity
├─ Your application: Guides surveillance vs. treatment decisions
└─ Status: ✅ DIRECTLY CITED FROM NCCN

NOMOGRAMS AS RISK ASSESSMENT TOOLS:
├─ Source: NCCN Guidelines for Patients: Prostate Cancer (2026)
├─ Chapter 4: Assessing Your Risk
├─ What it says:
│  ├─ "A nomogram predicts your prognosis, which is the likely
│  │  course your cancer will take"
│  ├─ "A nomogram uses math to compare you and your prostate
│  │  cancer to hundreds or thousands of other people who have
│  │  been treated for prostate cancer"
│  ├─ "Your doctor can use a nomogram to predict how likely
│  │  your cancer is to grow or spread, based on your test
│  │  results"
│  └─ "Risk groups and nomograms both provide information that
│  │  is specific to you, but nomograms can give slightly more
│  │  accurate estimates of cancer risk"
├─ Your application: MSKCC Post-RARP Nomogram for recurrence risk
└─ Status: ✅ DIRECTLY CITED FROM NCCN
│  (but specific coefficient values NOT in my sources)

SECTION 5: SIDE EFFECTS & QUALITY OF LIFE

✅ WHAT I CITED FROM NCCN GUIDELINES

RADICAL PROSTATECTOMY SIDE EFFECTS:
├─ Source: NCCN Guidelines for Patients: Prostate Cancer (2026)
├─ Chapter 5: Regional Prostate Cancer Treatment
├─ What it says:
│  ├─ "Possible side effects of radical prostatectomy can include
│  │  urinary incontinence and erectile dysfunction"
│  ├─ "Urinary incontinence (being unable to hold your urine) is
│  │  usually temporary. Most people gradually recover control of
│  │  their bladder after a few months or so"
│  ├─ "Doing exercises to strengthen the pelvic floor can help"
│  ├─ "Erectile dysfunction may slowly improve over several
│  │  months to 2 years after the surgery. However, you may
│  │  never regain the same erectile function you once had"
│  ├─ "Treatment options include pills (like Viagra and Cialis),
│  │  injections of medication into the penis, vacuum
│  │  constriction devices (penis pump), and surgical implants
│  │  that produce an erection"
│  └─ "Erectile dysfunction is a leading cause of depression in
│  │  people with prostate cancer. Ask your care team about
│  │  therapy or counseling if you're having any problems"
├─ Your application: Post-surgical recovery expectations
└─ Status: ✅ DIRECTLY CITED FROM NCCN

SUPPORTIVE CARE RECOMMENDATIONS:
├─ Source: NCCN Guidelines for Patients: Prostate Cancer (2026)
├─ Chapter 7: Supportive Care and Other Assistance
├─ What it says:
│  ├─ "Supportive care is for relieving symptoms and side effects,
│  │  and for other health issues related to cancer"
│  ├─ "Supportive care is given at any stage of disease, not just
│  │  at the end of life"
│  ├─ "Supportive care is treatment that involves the whole
│  │  person, not just their cancer"
│  ├─ "Many people with prostate cancer experience anxiety and
│  │  depression. Help is available"
│  └─ "A support group provides the opportunity to talk with
│  │  others who've been through a similar experiences"
├─ Your application: Managing post-surgical recovery
└─ Status: ✅ DIRECTLY CITED FROM NCCN

DISTRESS ASSESSMENT:
├─ Source: NCCN Guidelines for Patients: Prostate Cancer (2026)
├─ Chapter 3: Testing for Advanced-Stage Prostate Cancer
├─ What it says:
│  ├─ "Distress is mental, physical, social, or spiritual anxiety
│  │  or suffering"
│  ├─ "Distress is very common among people with cancer"
│  ├─ "If you're feeling distressed, tell your care team so they
│  │  can help you"
│  └─ Mentions distress thermometer scale (0-10)
├─ Your application: Emotional support during surveillance
└─ Status: ✅ DIRECTLY CITED FROM NCCN

SECTION 6: SURVEILLANCE & FOLLOW-UP PROTOCOLS

✅ WHAT I CITED FROM NCCN GUIDELINES

PSA TESTING SCHEDULE:
├─ Source: NCCN Guidelines for Patients: Prostate Cancer (2026)
├─ Multiple chapters reference surveillance protocols
├─ What it says:
│  ├─ "Tests are used to plan treatment and check how well
│  │  treatment is working"
│  ├─ "A high or rising amount of prostate-specific antigen (PSA)
│  │  in the bloodstream may be a sign of prostate cancer"
│  ├─ "Monitoring involves periodic PSA tests and sometimes
│  │  digital rectal exams"
│  └─ Specific frequencies vary by risk group and time since
│  │  treatment
├─ Your application: Lifelong PSA surveillance after surgery
└─ Status: ✅ DIRECTLY CITED FROM NCCN

IMAGING SURVEILLANCE:
├─ Source: NCCN Guidelines for Patients: Prostate Cancer (2026)
├─ Chapter 3: Testing for Advanced-Stage Prostate Cancer
├─ What it says:
│  ├─ "Imaging tests are used after cancer treatment to see how
│  │  well

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