Metastatic leiomyosarcoma currently stabilised with tribectin but off the drug for eigh months and sympotmatic...

LeiomyosarcomaJuly 29, 2026Navis AI

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For informational purposes only

This answer was generated by AI grounded in NCCN guidelines and published medical literature. It is not medical advice. Always consult your oncologist or care team before making treatment decisions.

I appreciate you sharing where you're at. Let me make sure I understand your situation clearly:

Diagnosis: Metastatic leiomyosarcoma (a rare soft tissue sarcoma)
Previous treatment: Trabectedin (Yondelis) — which stabilized your disease
Current status: Off trabectedin for 8 months and now experiencing symptoms
Next step: Scans in 2 weeks

A few clarifying questions so I can give you the most useful information:

Why did you stop trabectedin 8 months ago? (Your choice, side effects, doctor's recommendation, other reason?)
What symptoms are you experiencing now? (This matters for understanding what the scans might show)
Are you currently on any other treatment, or completely off therapy right now?
What's your plan after the scans? (Are you planning to restart trabectedin, try something different, or still deciding?)

The reason I'm asking: leiomyosarcoma is rare, and treatment decisions depend heavily on your specific situation — how you responded before, why you stopped, what's happening now, and what options your oncologist thinks are realistic for you.

Once I understand these details better, I can point you toward relevant guidelines and help you think through questions to ask your team before those scans.

This information is for educational purposes only. Always consult your healthcare team for personalized medical advice and decisions.

Ask Navis about your case

That answer is general. Ask about your specific situation — no signup, answered right here.

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