How do I deal with changes in taste and smell during Colorectal Cancer treatment

Colorectal CancerMay 17, 2026Navis AI

For informational purposes only

This answer was generated by AI grounded in NCCN guidelines and published medical literature. It is not medical advice. Always consult your oncologist or care team before making treatment decisions.

Managing Taste and Smell Changes During Colorectal Cancer Treatment

Taste and smell changes are common side effects during cancer treatment, and the good news is there are practical strategies to help you manage them.

Why This Happens

Chemotherapy and other cancer treatments attack rapidly dividing cells throughout your body—including the cells in your mouth, throat, and the sensory receptors that detect taste and smell. This can cause foods to taste metallic, bland, or completely different than you remember. Some patients also experience changes in smell, which directly affects how food tastes (since much of what we perceive as "taste" actually comes from smell).

Practical Strategies to Try

Experiment with flavors and seasonings:

  • If foods taste bland or unappetizing, try adding seasonings you may not have used before
  • Use herbs and spices to enhance nutrient absorption and make meals more enjoyable
  • Don't be afraid to try unexpected flavor combinations—what appeals to you may surprise you

Focus on texture and temperature:

  • Try cold foods, which may taste better than warm foods during treatment
  • Experiment with different textures (soft, crunchy, smooth) to find what's most appealing
  • Use a straw when drinking beverages, which can change how flavors reach your taste buds

Prioritize protein and calories:

  • Eat several small meals throughout the day rather than three large ones
  • Focus first on getting enough protein, which is essential for recovery
  • If you can only manage small amounts, choose calorie-dense foods like nut butter, fatty fish, or avocados
  • Nutritional drinks (like Ensure or Boost) can help you get calories and nutrients without relying on solid food

Keep a food diary:

  • Write down what you eat and how it tastes to you
  • Note which foods make you feel better and which ones don't appeal to you
  • Share this information with your care team—it helps them understand your specific situation

Important Caution

Avoid eating your favorite foods when you feel worst. If you eat something you love while feeling nauseous or unwell, you may develop a negative association with that food and never want to eat it again. Save your favorite foods for when you're feeling better.

When to Ask for Help

If taste changes are making it difficult to eat enough:

  • Talk to your oncology team about appetite-stimulating medications
  • Ask for a referral to a registered dietitian who specializes in cancer care—they can provide personalized nutrition strategies
  • Let your care team know if you're losing weight or struggling to maintain adequate nutrition

Questions to Ask Your Healthcare Team

  1. Are there specific foods I should avoid or prioritize given my treatment plan?
  2. Should I see a dietitian to help manage taste changes and maintain nutrition?
  3. Are there medications that can help if taste changes are affecting my appetite?
  4. How long do taste changes typically last after my treatment ends?
  5. What signs should I watch for that indicate I'm not getting enough nutrition?

This information is for educational purposes only. Always consult your healthcare team for personalized medical advice and decisions.

This is general information.

Upload your records for guidance specific to YOUR diagnosis — personalized to your biomarkers, stage, and treatment history.

Get guidance specific to your case

This answer covers general information. For guidance based on YOUR records, biomarkers, and treatment history: