How about grade 3b specifically? want to know about that

Based on the provided NCCN Guidelines for Diffuse Large B-Cell Lymphomas (2025), I can provide some specific information about Follicular Lymphoma Grade 3B (FL3B):

According to the NCCN Guidelines, FL3B is specifically listed as one of the types of large B-cell lymphomas (LBCLs) and is also referred to as "Follicular lymphoma grade 3B (FL3B)/FLBCL" in Guide 1 of the document.

However, the provided guideline excerpts don't contain detailed specific information about FL3B's characteristics or treatment. To provide accurate, evidence-based information about FL3B specifically, we would need additional sections of the NCCN Guidelines or other authorized sources from the approved list.

For proper diagnosis of any LBCL subtype, including FL3B, the NCCN Guidelines indicate these key diagnostic steps are required:

1. Biopsy with hematopathology review
2. Immunophenotyping including:

• IHC panel (CD3, CD20, CD10, CD21, BCL2, BCL6, IRF4/MUM1, and MYC)
• Flow cytometry analysis

1. Additional testing as needed to determine specific LBCL subtype

I recommend consulting with your healthcare team for more specific information about FL3B, as they can access the complete guidelines and provide guidance relevant to your specific situation.

Source: NCCN Guidelines for Patients®: Diffuse Large B-Cell Lymphomas, 2025