Hello! Recently had an ultrasound and mammogram upon finding a lump under my armpit. The results from the...

LymphomaOctober 3, 2026Navis AI

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This answer was generated by AI grounded in NCCN guidelines and published medical literature. It is not medical advice. Always consult your oncologist or care team before making treatment decisions.

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Question asked:

Hello! Recently had an ultrasound and mammogram upon finding a lump under my armpit. The results from the ultrasound: enlarged axillary lymph node is seen with cortical thickening up to 1.1 cm. Node is hyperechoic, with adjacent infiltrative appearing irregular hypoechoic area with internal...

Understanding Your Ultrasound Results

I can help you understand what these findings mean in plain language. However, I want to note upfront that you mentioned having lymphoma in your medical history, which is important context for interpreting these results. Let me explain what the radiologist observed:

What Your Ultrasound Shows

Enlarged axillary lymph node with cortical thickening (1.1 cm):

  • Your lymph node under your arm (axillary region) is larger than normal
  • The outer layer (cortex) of the node is thickened, which can suggest the node is reactive (responding to something) or potentially involved with lymphoma
  • The 1.1 cm measurement is the thickness of this outer layer

Hyperechoic appearance:

  • This means the node appears brighter on ultrasound, which can indicate various conditions including inflammation, infection, or lymphoma involvement

Irregular hypoechoic area with infiltrative appearance:

  • There's an area within or near the node that looks different—darker and irregular
  • "Infiltrative" suggests something is spreading into the surrounding tissue
  • This finding warrants further evaluation

Important Context for Your Situation

Given your lymphoma history, these findings take on specific significance. According to NCCN Guidelines for Hodgkin Lymphoma, imaging plays a crucial role in monitoring lymphoma patients, particularly:

  • PET/CT scans are the standard imaging used to determine if lymphoma is present or has returned, as they're more specific than ultrasound alone
  • Ultrasound can identify enlarged nodes, but PET/CT provides better information about whether nodes are involved with active lymphoma

What You Should Do Next

Questions to ask your oncology team:

  1. "Do these ultrasound findings suggest my lymphoma may have returned, or could this be something else like an infection or reactive lymph node?"

  2. "Should I have a PET/CT scan to better evaluate this area?" (PET/CT is the standard imaging per NCCN Guidelines for assessing lymphoma)

  3. "Based on my lymphoma history and treatment, what's your interpretation of these findings?"

  4. "Do you recommend a biopsy of this node, or will imaging be sufficient?"

  5. "What's the timeline for follow-up imaging or evaluation?"

Why This Matters

The combination of an enlarged node with cortical thickening and an irregular infiltrative area could suggest lymphoma involvement, but it could also represent:

  • Reactive lymphadenopathy (swollen nodes from infection or inflammation)
  • Other benign conditions
  • Recurrent lymphoma (if you're in remission)

Your oncologist needs to integrate this ultrasound finding with your complete clinical picture—your treatment history, current symptoms, lab work, and potentially PET/CT imaging—to determine what's actually happening.

Next Steps

Don't wait on this. Contact your oncology team with these ultrasound results if you haven't already. They may want to:

  • Review the images themselves
  • Order additional imaging (PET/CT is standard per NCCN Guidelines)
  • Possibly perform a biopsy if imaging is inconclusive

According to NCCN Guidelines for Hodgkin Lymphoma, PET/CT imaging plays a key role in determining the stage of disease and monitoring for recurrence, so this is likely the next appropriate step.


This information is for educational purposes only. Always consult your healthcare team for personalized medical advice and decisions.

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