Protean Methylation

Methylation testing that helps classify a cancer and identify where a tumor started.

Vetted listingTakes insuranceFinancial aid available

Diagnostics

Consented intake · your records travel with you · nothing moves without your sign-off

Why Protean exists

Protean Methylation offers epigenetic testing that examines DNA methylation patterns to classify cancer and identify a tumor's origin. It is for patients and care teams who need clearer answers about what kind of cancer they are dealing with. Knowing the tumor type and where it started can shape which treatment paths make sense to discuss.

5 to 10 business daysCAP · Accredited laboratoryCLIA · Certified laboratoryPennsylvania DOH · Laboratory permitNew York State DOH · Laboratory permit

1
Complete the CNS requisition form
The ordering physician completes the CNS test requisition form.
2
Send the form
The completed form is sent by fax or through the secure electronic portal.
3
Ship tissue or slides
FFPE tissue block or 20 unstained slides are shipped with the pathology report. Overnight shipping is required for tissue blocks; regular shipping for slides.
4
Receive results
Results are returned within 5 to 10 business days.

Prefer the source? Protean Methylation's own site has more.

Share your records

We package your records and pre-fill the Protean Methylation intake — no retyping.

Start sharing →

Check your coverage

See if your insurance covers this and estimate out-of-pocket cost.

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Coverage, insurance & cost

The fastest way to know what you'll pay: check your coverage with your plan. Below is what we know about how Protean Methylation handles billing.

Insurance

Accepted

Financial aid

Available

Prior auth

Required

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Common questions about Protean

Does Protean take insurance?

Protean accepts insurance; financial assistance is available. Add your plan on OpenCancer to check coverage before you commit.

How does Protean work?

1. Complete the CNS requisition form — The ordering physician completes the CNS test requisition form. 2. Send the form — The completed form is sent by fax or through the secure electronic portal. 3. Ship tissue or slides — FFPE tissue block or 20 unstained slides are shipped with the pathology report. Overnight shipping is required for tissue blocks; regular shipping for slides. 4. Receive results — Results are returned within 5 to 10 business days.

How long does Protean take?

5 to 10 business days

How do I connect with Protean?

Through OpenCancer's consented intake: enter your details once, choose exactly which records travel with the request, and sign a consent that covers this connection only. Nothing is shared without your sign-off.

Understand this before you decide

Epigenetic profiling sample report (PDF)

Guide from Protean Methylation

Ask about this service

Answers grounded in Protean's details here. Educational only; your oncologist directs treatment.

Who this is for

Cancer types served

braincolorectallungpancreatic

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