Why Olink exists
Olink offers proteomics, the mapping and analysis of proteins, using plasma as input. The approach models the signature pathways of cancer cells to identify biomarkers that may inform treatment. Olink's offering is for research use only, which matters for patients deciding now: it can add insight, but it is not a clinical diagnostic service.
- 1
Immuno reaction
Two matched antibodies labeled with unique DNA oligonucleotides bind to a target protein in solution.
- 2
Extension
Once in proximity, the DNA oligos hybridize and are extended by DNA polymerase, creating a DNA barcode unique to each protein.
- 3
Detection
The DNA barcode is amplified by PCR, generating a signal that is measured by next generation sequencing or qPCR.
Prefer the source? Olink (RUO, plasma)'s own site has more.
