Why C2i exists
C2i Genomics provides liquid biopsy testing focused on minimum residual disease. It gathers and analyzes blood and other bodily fluids for biomarkers such as DNA, RNA, and proteins that can guide treatment and monitor disease progression. For patients wanting to know whether cancer remains after treatment, this kind of monitoring provides ongoing insight.
- 1
Tissue and blood collection
Blood and tissue samples are submitted. Blood is separated into plasma for ctDNA analysis and buffy coat for a normal germline comparison, alongside the tumor tissue sample.
- 2
Create the tumor signature
Whole genome sequencing analyzes DNA from the tumor tissue and from normal germline cells to identify the cancer specific mutations that form a personalized tumor signature.
- 3
Establish a baseline
Whole genome sequencing of the plasma sample creates a baseline result that future tests are compared against.
- 4
Monitor for recurrence
Blood samples collected at later timepoints are compared to the baseline, delivering an estimated tumor fraction and a clear Detected or Not Detected result.
Prefer the source? C2i Genomics (MRD)'s own site has more.
