“Solving Information Inequities between Cancer Patients, their Doctors, and Clinical Trial Sponsors”

nstructured text that makes finding relevant trials challenging. With about 13,000 active cancer trials, you can feel overwhelmed and discouraged by the sheer number of options and struggle to parse through trial possibilities and understand how your specific condition matches potential trials.

“Solving Information Inequities between Cancer Patients, their Doctors, and Clinical Trial Sponsors” (Mike Harris) [#136] ●Limited help: About 75% of patients are interested in clinical trials, but only 20% feel adequately informed by their doctors. Doctors are often unaware of trials happening at nearby hospitals, with many not proactively searching for trial options for their patients.

●Geography/access : Most clinical trials are run at academic hospitals, but only 20% of patients are treated at these institutions, creating significant access challenges. ●Overcoming hesitancy : Feeling unsure about being the subject of an experiment. How should services to help patients and doctors find relevant clinical trials be designed?

●Patient-friendly: Make clinical trial information easy for patients to understand, reducing information inequities with doctors and trial sponsors. ●Doctor-friendly: Quickly find relevant clinical trials for their patients, without additional administrative burden. ●Easy to access: Minimize upfront personal medical information entry.

●Personalized: Find relevant trials based on patient-specific criteria, such as cancer stage, biomarkers, geography, and treatment history. ●Shared decision-making : Able to easily share information and search results (patient and medical team). ●Unbiased: Don’t favor the institution where you happen to be. ●Continuous: Scan and share dynamic, changing information, e.g., new slots in a trial.

How can artificial intelligence enhance clinical trial recommendations? ●Match: Review unstructured text in your medical records against clinical trial inclusion/exclusion criteria and specific medical requirements (like liver or kidney function). ●Administer: Extract your key medical information for trial enrollment. ●Personalize: Tailor the information output to you, e.g., language.

How can you learn more about services for navigating your cancer care?

●See our previous conversations on the design of cancer navigation services, such as: ○“Helping Patients Navigate Cancer” (Manta Cares) [#93] ○“Review of Services for Glioblastoma Navigation” (Mike Pyne) [#92] ○“Expert Patient Navigation” (Deb Christensen, MSN, APRN) [#99] ○“Patient Navigators: Your Guide through the Clinical Trial Journey” (Madeleine Carrier, PharmD, and Dennis Akkaya) [#104] ○"Illuminating the Path of Cancer Care with a Chatbot" (Vanessa Liu, CareBud) [#82] ○“Introducing an app for navigating cancer care” (Berries) [#67] ●Contact Mike Harris at mike.

harris@tricanhealth.com.

lluminating the Path of Cancer Care with a Chatbot" (Vanessa Liu, CareBud) [#82] ○“Introducing an app for navigating cancer care” (Berries) [#67] ●Contact Mike Harris at mike.harris@tricanhealth.com.

The information and opinions expressed on this website or platform, or during discussions and presentations (both verbal and written) are not intended as health care recommendations or medical advice by Cancer Patient Lab, its principals, presenters, participants, or representatives for any medical treatment, product, or course of action.

“Solving Information Inequities between Cancer Patients, their Doctors, and Clinical Trial Sponsors” (Mike Harris) [#136] specific situation before pursuing any health care program, treatment, product or other course of action that might affect your health.

“Solving Information Inequities between Cancer Patients, their Doctors, and Clinical Trial Sponsors” (Mike Harris) [#136] Meeting Notes KEYWORDS Clinical trials, pancreatic cancer, patient navigation, trial matching, clinicaltrials.

gov, patient information, trial enrollment, biomarkers, personalized medicine, patient-physician communication, trial sponsors, AI enhancement, patient advocacy, trial accessibility, treatment options.

SPEAKERS Mike Harris (86%), Brad Power (6%), Kathi Peterson (3%), Cindy Ness (2%), Raj Aji (2%), Rob Weker (1%), Eric Dishman (0%) SUMMARY Mike Harris from Trican Health discussed their new clinical trial matching platform focused on pancreatic cancer patients in the U.S. The platform, which uses clinicaltrials.gov data, aims to simplify trial information and make it more accessible.

It allows patients to search for trials based on their specific conditions and location, providing a trial snapshot with key details. Harris emphasized the platform's unbiased approach, aiming to bridge information gaps between patients, physicians, and trial sponsors. The platform also plans to expand to other cancers and integrate AI to enhance search accuracy.

The discussion highlighted the challenges of trial access and the need for better patient-physician communication. OUTLINE Introductions ●The focus is on clinical trial matching for various cancers, particularly pancreatic cancer. ●Mike Harris from Trican Health discussed their new clinical trial matching platform.

Overview of Trican Health and Platform Goals ●Trican Health is a digital platform aimed at helping pancreatic cancer patients make informed treatment decisions. ●It uses clinicaltrials.gov as its primary source of information, augmenting it with supplemental data to make it more accessible.

●It aims to provide an unbiased, patient-centric, and comprehensive service, free for patients and physicians. ●They plan to expand its services to other forms of cancer in the future.

sed, patient-centric, and comprehensive service, free for patients and physicians. ●They plan to expand its services to other forms of cancer in the future. Detailed Platform Features and Demonstration ●The platform's features include navigation for clinical trials, disease information, and trial availability. ●It is designed to be accessible to both knowledgeable and less knowledgeable patients, with options for targeted searches.

“Solving Information Inequities between Cancer Patients, their Doctors, and Clinical Trial Sponsors” (Mike Harris) [#136] ●Mike Harris demonstrated the platform, showing how patients can search for trials based on their specific conditions and location.

●The platform provides a trial snapshot with key information, including trial status, summary, biomarkers, trial design, location, line of therapy, and contact information. Challenges and Opportunities in Clinical Trial Matching ●The challenges patients face in accessing clinical trials include limited information from doctors and the lack of awareness about available trials.

●The platform aims to bridge gaps between patients, physicians, and clinical trial sponsors, making the process more efficient and effective. ●Making clinical trial information accessible to patients in remote areas and those treated at non-academic hospitals is important.

●The platform also aims to help patients find additional resources, such as financial and logistical assistance, to support their treatment journey. ●Carefully handling personal information is important in building trust. ●Feedback is needed from users to continuously improve the platform and make it more effective for patients and physicians.

Live Demonstration and Personalized Search ●Mike Harris demonstrated a live search for a pancreatic cancer patient, Kathi Peterson, using her specific conditions and location. ●The search results show a narrowed list of trials that were relevant and accessible to Kathi, highlighting the platform's ability to provide personalized recommendations.

●Mike explained the process of saving and sharing trial information with physicians and family members for further discussion. ●The demonstration underscored the platform's potential to help patients and physicians make informed decisions about clinical trials.

Final Thoughts and Call to Action ●Mike summarized the platform's goals and the importance of reducing information inequities between patients, doctors, and clinical trial sponsors. ●The platform aims to make advanced medicine more accessible and to support shared decision-making between patients and physicians.

●Mike encouraged the audience to share the platform with others and to provide feedback to help improve the service. ●The meeting concluded with a QR code for accessing the platform and a reminder of the platform's mission to support pancreatic cancer patients.

“Solving Information Inequities between Cancer Patients, their Doctors, and

latform with others and to provide feedback to help improve the service. ●The meeting concluded with a QR code for accessing the platform and a reminder of the platform's mission to support pancreatic cancer patients.

“Solving Information Inequities between Cancer Patients, their Doctors, and Clinical Trial Sponsors” (Mike Harris) [#136] TRANSCRIPT Brad Power This is the Cancer Patient Lab. This is our weekly webinar. Today we're honored to have Mike Harris of Trican Health with us. He's going to be talking about some new clinical trial matching around various cancers.

They are starting in pancreatic cancer, but I'm sure he will explain that is probably just a beachhead for broader things, so you can talk about where they're going in the future. I want to cover our standard housekeeping items. The first is that this is for medical information only. This is not medical advice. We try to arm our patients with information they can take to their medical team.

The second is that everything here will be made public, we’re very open source. If you’re concerned about having your image, name, or words shared, you can change your name, image, and not verbally participate. Finally, We are a nonprofit 501(c)(3), and we depend on the kindness of volunteers and donors.

If you're inspired to donate, that's easily done through our website, where there's a Donate button, and we're always looking for volunteers. With that, I’ll turn it over to Mike. Mike Harris 1:17 I'd like to review with you what we're doing within Trican Health. You can see the URL here.

I'd like to define what we are, and what we're not, and then step through some information of what we're doing and why we're doing it.

“Solving Information Inequities between Cancer Patients, their Doctors, and Clinical Trial Sponsors” (Mike Harris) [#136] someone in Kathi Peterson who's working through pancreatic cancer right now. If she's willing, we might be able to do a live search based on her specific conditions, and give you a sense of how the platform would work.

As Brad suggested, this is a specific focus right now in pancreatic cancer in the United States, but we are intending to expand to other forms of cancer as we expand the platform. Trican is a digital platform, similar to Cancer Patient Lab, in terms of providing information and insight. Our goal is to help patients make informed decisions throughout their treatment journey.

We are specifically servicing pancreatic cancer patients in the US. We have capabilities to provide navigation for clinical trials, so understanding more about clinical trials, information about the disease, how clinical trials work (and how they don't). We want to make things easy to access and understand from a clinical trial availability perspective.

This is an exceptionally knowledgeable group of patients and practitioners today.