“Exercise to Boost Your Immune System to Fight Cancer”
Featuring: Dr. Tom Incledon
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Dr. Tom Incledon
“Exercise to Boost Your Immune System to Fight Cancer” (Dr. Tom Incledon) [#49] Brad Power March 22, 2023 “You're going about the exercise portion in the context of everything else that's going on.” – Dr.
Tom Incledon “When I look at all the different drugs and supplements and strategies that have been tried, I've not found anything that comes even close to stimulating the increases in natural killer cells and cytotoxic T lymphocytes [as exercise with oxygen therapy].” – Dr.
Tom Incledon Meeting Summary In their search for therapies that can fight their advanced cancer, patients and caregivers are moving beyond the standard of care of surgery, radiation, chemotherapy, and immunotherapy to explore "Food as Medicine" and "Exercise as Medicine.
" Exercise can offset the effects of hormone deprivation therapies on weight, strengthen the heart, increase bone strength, and raise resilience. But is there scientific evidence that can measure the impact of exercise, and point to some exercise therapies that are better than others? Since 1989, Thomas Incledon, PhD, RD, known to most as “Dr.
Tom”, has been recognized as one of the world’s leading experts in human health and athletic performance. He is the founder and CEO of Causenta Wellness, a cutting-edge wellness and cancer treatment center in Scottsdale, Arizona. He holds a B.S. in Exercise Science, B.S. in Nutrition, M.S. in Kinesiology, and Ph.D. in Exercise Physiology. “The World’s Strongest Sports Scientist,” Dr.
Tom has competed at the World Championship level and set national records in Strongman Competitions. Dr. Tom sets the stage for any exercise program to make sure that it is personalized to the individual. A patient should get a battery of tests that a patient before starting an exercise program.
His research has uncovered an approach that is very beneficial for cancer patients: exercise with oxygen therapy, which improves the immune system to fight cancer and simultaneously makes patients significantly stronger. What are the benefits of exercise? Any exercise is beneficial. It reduces the cancer burden in the body. More exercise in all forms is always good.
Exercise strengthens the immune system (increases cytotoxic T lymphocytes and NK cells) in healthy people and people with cancer. You can simultaneously improve your brain, heart, lung, and muscle function. You can enhance recovery and reduce inflammation markers faster.
“Exercise to Boost Your Immune System to Fight Cancer” (Dr. Tom Incledon) [#49] Some drugs that you may be taking, such as chemotherapy, will reduce the immune response to exercise. What testing is needed to set the context for an exercise program? Testing must be done to set the stage for an exercise regimen so that you have a game plan, rather than just doing some exercises.
sting must be done to set the stage for an exercise regimen so that you have a game plan, rather than just doing some exercises. Before you start an exercise program you should test, analyze, and understand your: ●Genome: Understanding the DNA and RNA mutations in your tumor tissue and blood is a good start, but they are not a guarantee that's what's driving the cancer.
●Proteome: Proteomics (analysis of the proteins in your tumor) are going to add to your understanding of your cancer. ●Environmental chemicals : Can disrupt your endocrine function and prevent chemotherapy and immunotherapy from working.
●Microbiome ●Micronutrients: You should understand a wide range of vitamins and minerals, essential amino acids, essential fatty acids, and other antioxidants that impact immune system (lymphocyte) responses. Dr. Tom works primarily with Tempus Labs (for somatic mutation testing) and mProbe (for proteomic testing) and other labs for additional testing services.
What are other principles in designing an exercise program? Your exercises should address what is limiting you. For example, if you have trouble getting up and have weakness in your left leg, you should work on strengthening your left leg. If you are at a low level of fitness, e.g.
, you can't stand, or can't walk, and results are needed fairly quickly for survival, then you should take an aggressive approach to exercise, including supplementing with oxygen. If you are at higher levels of fitness, then high intensity interval training is very effective. You should plan to progress in your fitness to get a stronger immune response.
You should set goals to do more work and have less rest in the same amount of time. For example, if you're burning 10 calories a minute, then go to 11, 12, and 13. You should set a minimum goal to do 1000 calories in a workout. At that level of exercise you won’t have any brain, heart, or lung risks.
If you are doing sprints or intervals, you should measure your response and recovery, looking at your heart rate and blood pressure afterwards. For example, if it's taking you four minutes to recover, then the exercise stimulus was too much at your current level. Increasing or lowering oxygen concentration can enhance the desired effects of your exercise.
For example, to enhance brain, heart, lung, and immune system function, you should add oxygen to your exercise. To add muscle faster, you should reduce oxygen.
“Exercise to Boost Your Immune System to Fight Cancer” (Dr. Tom Incledon) [#49] How does taking oxygen during exercise increase the impact of exercise on your immune system? ●Exercising with oxygen allows you to do up to 25% more work. This extra work increases your epinephrine, which stimulates your immune system cells (cytotoxic T lymphocytes and NK cells). ●Exercise with oxygen appears to eliminate pathogens in the blood. How do you increase or reduce oxygen during exercise?
with oxygen allows you to do up to 25% more work. This extra work increases your epinephrine, which stimulates your immune system cells (cytotoxic T lymphocytes and NK cells). ●Exercise with oxygen appears to eliminate pathogens in the blood. How do you increase or reduce oxygen during exercise? For increasing oxygen, you wear a mask and breathe through a hose while you are exercising.
The hose is connected to a bag which is connected to an oxygen concentrator, which takes room air and concentrates the oxygen. For reducing oxygen, there are tools that restrict blood flow to the working muscle. You can get velcro cinch straps from Amazon for about $16 to $20. They are small enough to fit around your arm or the top of your thigh.
You pull it tight, and then put the velcro attachment on, and it holds the occlusion over, for example, a blood vessel in the upper arm. How can you access oxygen therapy? You don't have to go to Arizona. You fill out a form on a website. Once you have your lab results, you have an initial consultation. There is no charge for the first consultation. Most people do it by Zoom.
It's 30 minutes long. You go over your case, and they point you in the right direction. Beyond the initial consultation, additional consulting is $360 an hour, which provides recommendations, such as additional tests. An exercise with oxygen therapy session is $150. Some people buy packages of 12 for $1500.
The information and opinions expressed on this website or platform, or during discussions and presentations (both verbal and written) are not intended as health care recommendations or medical advice by Cancer Patient Lab/Prostate Cancer Lab, its principals, presenters, participants, or representatives for any medical treatment, product, or course of action.
You should always consult a doctor about your specific situation before pursuing any health care program, treatment, product or other course of action that might affect your health.
“Exercise to Boost Your Immune System to Fight Cancer” (Dr.
Tom Incledon) [#49] Meeting Notes The information and opinions expressed on this website or platform, or during discussions and presentations (both verbal and written) are not intended as health care recommendations or medical advice by Prostate Cancer Lab, its principals, presenters, participants, or representatives for any medical treatment, product, or course of action.
You should always consult a doctor about your specific situation before pursuing any health care program, treatment, product or other course of action that might affect your health. Discussion Outline 1.Introduction to exercise for prostate cancer. (0:03) 2.How do you know if you’re on the right track? (4:32) 3.Environmental chemicals and the microbiome. (9:54) 4.Oxygen concentrator and exercise.
(15:37) 5.Bacteria in the blood. (21:05) 6.How many sessions of exercise did this patient have? (25:54) 7.Exercises and immune function. (31:41) 8.
(0:03) 2.How do you know if you’re on the right track? (4:32) 3.Environmental chemicals and the microbiome. (9:54) 4.Oxygen concentrator and exercise. (15:37) 5.Bacteria in the blood. (21:05) 6.How many sessions of exercise did this patient have? (25:54) 7.Exercises and immune function. (31:41) 8.Questions and answers about access to treatment. (36:25) 9.Is exercise like a placebo for cancer?
(42:03) 10.Exercise’s long-term benefits. (46:22) 11.What is the cost of treatment? (50:47) 12.What is the cost of an EWOT session? (55:18) 13.Oxygen concentrators and oxygen consumption. (1:00:30) 14.Work-to-rest ratio. (1:05:43) 15.PSA and prostate cancer treatment. (1:10:35) 16.Treatment recommendations for patients with stage IV.
(1:15:57) SUMMARY KEYWORDS exercise, people, testing, cancer, microbiome, organisms, minutes, data, patients, lab, bacteria, psa, supplemental oxygen, oxygen, increase, blood, therapies, immune responses, question, strategies SPEAKERS "Dr.
Tom” Incledon (81%), Brad Power (5%), Brian McCloskey (4%), Jim Ward (3%), Rick Stanton (2%), Saed Sayad (2%), Russ Holyer (2%), Amit Gattani (1%) Brad Power We're honored to have “Dr. Tom” Incledon with us today. We've had several sessions on exercise.
This was an interest for all of the prostate cancer patients because many are on androgen deprivation therapy, so they lose muscle, and they may have issues with heart health. Many people have weight issues one way or the other, needing to lose or gain weight. It seems like exercise is the treatment that just keeps on giving. Exercise is medicine.
“Exercise to Boost Your Immune System to Fight Cancer” (Dr. Tom Incledon) [#49] We've had a couple of sessions on exercise. Cathy Skinner talked about some of the exercises that she's used as she has coached people with cancer. We had Kerri Winters-Stone, a PhD researcher at OHSU who does research on exercise for musculoskeletal health. She gave us some of her research results and insights.
We met Dr. Tom because of his work in exercise for cancer, and the things that he's done given his background in exercise. We were particularly intrigued because he's running some of these things in a classic academic clinical trials background. He has a doctorate, and he's an academic as well as being a competitor in strength competitions – a very interesting combination.
We thought that he would have an interesting conversation with our community. "Dr. Tom" Incledon 3:33 I want to first provide a little bit of context for the exercise programs I prescribe.
“Exercise to Boost Your Immune System to Fight Cancer” (Dr. Tom Incledon) [#49] We're an integrative medical center. When we talk about exercise, it's in the context of everything else that we're doing. I wanted to go over what else we are doing here. One of the comical statements that a lot of my colleagues would say about me is that somehow I've
(Dr. Tom Incledon) [#49] We're an integrative medical center. When we talk about exercise, it's in the context of everything else that we're doing. I wanted to go over what else we are doing here.
One of the comical statements that a lot of my colleagues would say about me is that somehow I've managed to get oncologists, chiropractors, naturopaths, and homeopaths all on the same team working together without killing each other. Any one educational background realizes these worlds are so far apart, they see disease and health very differently.
I've tried to get people with various levels of educational bias and research backgrounds together. Imagine if you were on a football team and one guy has a certain offensive strategy and another guy has a different offensive strategy, then you put them on the same team. There'd be a lot of tension in that room. We've managed to get all these guys together on the same team.
It's enabled us to come up with really cool and unique strategies to the level that our cancer patients are gaining muscle, and specifically, our prostate cancer patients are gaining muscle. That's one measure. You might ask, “How do you know if you're going in the right direction when you're starting some therapy to treat the cancer?” Well, you shouldn't be losing your hair.
You shouldn't be getting weaker. You shouldn't be getting more frail.
“Exercise to Boost Your Immune System to Fight Cancer” (Dr. Tom Incledon) [#49] overall the strategy is not that effective. Because what will happen eventually is, if the cancer doesn't get you, the loss of all the muscle, the loss of the bone density, the loss of the ability to stand, well, that's going to do you in.
In order to prevent this from happening, I wanted to give you an overview of how we approach it. That way, you're not just hearing exercise out of context, but you're going about the exercise portion in the context of everything else that's going on. I'm summarizing data we've collected on over 200,000 people.
You're going to have to give me some privileges to make some conceptual leaps given the amount of time. If you were to simply Google, “How many gene tests does … do?” and fill in the blank, the lab could be Guardant, Foundation Medicine, Caris, Signatera, Tempus Labs, etc.
You could find in seconds that Tempus Labs right now is the number one lab for testing the greatest number of genes in tumor tissue. Why is that important? Because that then gives you more options for different treatments that are available as far as the genetics or genomic side.
You could also in a blood test, right now offering 105 genes, but they're pretty soon going to roll that up to 525 or 530 genes. Again, why does that matter? More treatment options right off the bat. You're not stuck with just treating the label of the disease like prostate cancer. You have other possibilities.
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