The AI stated that as it is now in the bone, this is called "bone marrow involvement" I didn't think that this is...

Follicular LymphomaApril 6, 2026Navis AI

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For informational purposes only

This answer was generated by AI grounded in NCCN guidelines and published medical literature. It is not medical advice. Always consult your oncologist or care team before making treatment decisions.

You're absolutely right to question that—thank you for catching that important distinction.

I made an error in my language. Let me clarify:


The Correct Distinction

Bone marrow involvement = lymphoma cells found IN the bone marrow itself (detected by bone marrow biopsy or aspiration)

Bone lesion/skeletal involvement = lymphoma tumor growing in the bone tissue itself (detected by imaging like PET scan or biopsy of the bone lesion)


What Your PET Scan Actually Shows

Your PET scan shows a bone lesion in your left femur—meaning the lymphoma tumor is growing in the bone tissue itself. This is skeletal involvement, not bone marrow involvement.

These are different:

  • Bone marrow involvement would require a bone marrow biopsy to diagnose
  • Bone lesion is visible on imaging (PET scan) and confirmed by tissue biopsy, as you have

According to the NCCN Guidelines for Patients: Follicular Lymphoma, bone marrow testing (bone marrow aspirate and biopsy) is done "depending on your situation" as part of initial staging and evaluation—but that's different from having an actual bone lesion visible on imaging.


Why This Distinction Matters

Your situation is: FL with skeletal involvement (bone lesion in femur) + lymph node involvement (neck and groin). This is important for your doctor to consider when choosing between systemic therapy (drugs throughout your body) versus localized radiation to the bone.

Thank you for keeping me accurate—these distinctions are clinically important.

This information is for educational purposes only. Always consult your healthcare team for personalized medical advice and decisions.

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