How do I find clinical trials for CLL

CLLMay 17, 2026Navis AI

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For informational purposes only

This answer was generated by AI grounded in NCCN guidelines and published medical literature. It is not medical advice. Always consult your oncologist or care team before making treatment decisions.

Sources & medical oversight

Grounded in NCCN Guidelines for Patients: Chronic Lymphocytic Leukemia — the same guidelines oncologists use.
Developed under the medical oversight of OpenCancer’s physician-scientist team (Chris Apfel, MD/PhD/MBA, CMO · Kaumudi Bhawe, PhD, CSO).
Last updated May 17, 2026. Informational only — not a substitute for your oncology team.

Finding Clinical Trials for CLL

I'm glad you're exploring clinical trial options—they can offer access to newer treatments and contribute to advancing CLL care. Here's a practical guide to finding trials that might be right for you.

Where to Search for CLL Clinical Trials

1. ClinicalTrials.gov (Primary Resource)

Go to www.clinicaltrials.gov
Search for "chronic lymphocytic leukemia" or "CLL"
Filter by:
- Location (your state/region)
- Trial status (recruiting, not yet recruiting)
- Phase (Phase 1, 2, 3, or 4)
- Sponsor (academic centers, pharmaceutical companies, NIH)

2. Cancer-Specific Trial Databases

National Cancer Institute (NCI): cancer.gov/about-cancer/treatment/clinical-trials
American Cancer Society: cancer.org/treatment/find-clinical-trials
Leukemia & Lymphoma Society: lls.org/clinical-trials (specifically focused on blood cancers like CLL)

3. Your Treatment Center

Ask your oncologist directly about trials they're running or know about
Many academic medical centers have dedicated clinical trial coordinators
Your hospital may have trials not yet listed on public databases

What to Look For in a CLL Trial

Key Information to Understand:

Trial Phase: Phase 1 (safety), Phase 2 (effectiveness), Phase 3 (comparison to standard treatment)
Eligibility criteria: Your disease stage, prior treatments, blood counts, organ function
Primary endpoint: What the trial is measuring (response rate, survival, side effects)
Treatment approach: Targeted therapy, immunotherapy, chemotherapy, or combination
Location and travel requirements: Some trials require frequent visits

Questions to Ask Your Oncologist About Trials

"Are there any CLL trials at our center or nearby that match my specific disease characteristics?"
"How does this trial's treatment compare to my current standard treatment options?"
"What are the potential benefits and risks specific to my situation?"
"What does participation involve—how often would I need to visit, and what tests are required?"
"Can I stop the trial if I experience side effects, and what happens to my care then?"

Important Considerations

You own your health data: According to guidance on patient data rights, you have the right to access your clinical trial data and understand how your information is being used
Informed consent is essential: Make sure you fully understand what participation means before enrolling
Standard care continues: Most trials don't replace your regular CLL treatment—they add to it or offer an alternative

Additional Resources

The Leukemia & Lymphoma Society (lls.org) is particularly valuable for CLL patients because they maintain disease-specific trial information and can connect you with patient advocates who've navigated trial participation.

According to NCCN Guidelines for CLL, clinical trials are considered an important treatment option at all stages of disease, especially for patients with relapsed or refractory CLL (disease that doesn't respond to standard treatment).

This information is for educational purposes only. Always consult your healthcare team for personalized medical advice and decisions.

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