After my first chemo cycle for stage 3 colon cancer, I got hit by an outbreak of shingles on my back, so i have that...
Ask Navis about your situation
This answer is general. Get one about your specific case. No signup, answered right here.
For informational purposes only
This answer was generated by AI grounded in NCCN guidelines and published medical literature. It is not medical advice. Always consult your oncologist or care team before making treatment decisions.
Sources & medical oversight
- Built by OpenCancer’s team of physician-scientists and cancer survivors.
- Last updated October 3, 2026. Informational only — not a substitute for your oncology team.
Question asked:
After my first chemo cycle for stage 3 colon cancer, I got hit by an outbreak of shingles on my back, so i have that to deal with as well ! Is this something common because of a compromised immune system, or a rare occurrence ? Thanks for your input.
Shingles After Chemotherapy: Understanding the Connection
I'm sorry you're dealing with both chemo side effects and shingles—that's a tough combination. The good news is that what you're experiencing is not rare at all. In fact, it's a recognized complication of cancer treatment.
Why Shingles Occurs During Chemotherapy
Here's what's happening: Chemotherapy works by targeting rapidly dividing cells (including cancer cells), but it also affects your immune system, particularly your white blood cells. This temporary immune suppression creates an opportunity for the varicella-zoster virus (the virus that causes chickenpox and shingles) to reactivate.
The key points:
- If you've ever had chickenpox, the virus remains dormant in nerve tissue for life
- When your immune system is weakened by chemo, that dormant virus can "wake up" and cause shingles
- This is a common side effect of cancer treatment, not a rare occurrence
- It typically appears 1-4 weeks after chemotherapy cycles
What This Means for Your Treatment
Important: You should report this to your oncology team immediately if you haven't already. Here's why:
- Timing matters - Your doctor may need to adjust your chemo schedule or manage the shingles aggressively to prevent complications
- Antiviral medications work best early - Drugs like acyclovir or valacyclovir are most effective when started within 72 hours of the rash appearing
- Pain management - Post-shingles nerve pain (called postherpetic neuralgia) can be significant, and your team can help prevent or minimize this
- Infection risk - Open shingles lesions can become infected, which is especially concerning with a compromised immune system
Questions to Ask Your Oncology Team
- Should we pause or adjust my chemo schedule while I'm treating the shingles?
- What antiviral medication do you recommend, and how long should I take it?
- How can we manage the pain from shingles while continuing treatment?
- Are there preventive measures I should take before my next chemo cycle (like the shingles vaccine)?
- What signs of complications should I watch for and report immediately?
Moving Forward
The combination of chemo and shingles is manageable, but it requires close coordination with your care team. Many cancer patients experience shingles during treatment and recover well with proper antiviral therapy and supportive care.
According to ASCO (American Society of Clinical Oncology) guidelines, managing infections and immune-related complications during cancer treatment is a standard part of your care plan, and your oncology team has protocols for exactly this situation.
This information is for educational purposes only. Always consult your healthcare team for personalized medical advice and decisions.
Ask Navis about your case
That answer is general. Ask about your specific situation. No signup, answered right here.
Facing this with someone you love?
Keep the whole picture in one private place: records, a plain-language summary of where things stand, questions, and the people helping. Navis keeps it up to date so no one has to re-explain the story. Free, and only the people you invite can ever see it.
Start a care circle →Related Services
Services that may help with diagnosis for cancer patients
Have your records handy? Upload them for a deeper, personalized analysis →
Related Questions
Has anyone ever gotten blood clots in or around there lungs ? They just found 2 in mine about a week ago, this is...
I'm truly sorry you're dealing with this—pulmonary embolism blood clots in the lungs is serious and painful, and your experience is unfortunately not
Oh the joys of side effects. I stopped chemo about 3 weeks ago and have had one infusion of immunotherapy since....
I hear you—that throat sensation is really uncomfortable, even when it's not painful. Before I suggest anything, I need to ask a few clarifying questi
Had my second surgery about 3 weeks ago to treat thyroid cancer (this surgery was for reoccurrence in the lymph...
I'd be happy to help you understand what you're experiencing! Those white bumps after neck surgery can be a few different things, and it's good you're
My husband just had his 3rd shot for adjuvant Capox. he's been sleeping most of the time after that. Like today he...
Yes, what you're describing is a very common side effect of Capox chemotherapy, and it's important to understand what's happening and when to be conce
Tomorrow my best friend starts infusion chemo she has Invasive Ductal Carcinoma breast cancer what are some things...
I'm glad you're being such a supportive friend. Here's practical information to help her prepare for infusion chemotherapy: BEFORE HER FIRST TREATME
Starting chemo for peritoneal cancer next week. Anyone have any advice to make it more tolerable? Please & thank you!
I'm glad you're reaching out—preparing for chemotherapy can help you feel more in control. Here are evidence-based strategies that many patients find
Chemo support Hi everyone — I’m hoping to connect with caregivers or families who have been through chemo with a...
I can see you're looking for peer support and community connection—that's really important, and I want to help point you in the right direction. Howe
Welp, just when I thought I was doing good, the cancer bug comes back and now it’s in some of my lymph nodes. Doc...
I'm sorry you're dealing with a recurrence—that's a tough situation, and it's completely understandable to feel concerned about what's ahead. Let me h