About this document "ALK/ROS1/RET fusions (NGS)": How much does ALK/ROS1/RET fusions (NGS) typically cost

Based on the document provided, the exact cost of ALK/ROS1/RET fusion testing using NGS (Next Generation Sequencing) is listed as "Varies." The document doesn't specify a precise dollar amount.

However, I can provide some important context about coverage:

1. According to the document, this test is covered by insurance, which is a significant factor for patients.

2. According to the NCCN 2024 Guidelines (referenced in the document), molecular testing for these fusions is considered standard of care for metastatic non-squamous NSCLC patients, which supports insurance coverage.

3. The American Society of Clinical Oncology (ASCO) guidelines recommend biomarker testing, including ALK, ROS1, and RET, as essential for directing appropriate therapy in advanced NSCLC patients.

Since the actual out-of-pocket cost can vary significantly based on:

• Insurance coverage
• Laboratory performing the test
• Geographic location
• Specific testing panel used

I would recommend:

1. Checking with your specific insurance provider about coverage
2. Discussing with your healthcare team about which laboratory they use
3. Asking about financial assistance programs if needed

Sources:

• NCCN Guidelines 2024 (as referenced in document)
• ASCO Guidelines for Molecular Testing in Lung Cancer
• American Cancer Society's recommendations for biomarker testing in lung cancer